Orthopedic Clinical Evidence

Clinical Data- Acoustic Pressure Waves in Medicine

Clinical Papers

These articles offer insight into the uses and benefits of non-surgical approaches in the field of orthopedics.

Please note: Some of the information contained in the articles listed may pertain to products, indications for use of products and/or treatments/ procedures that are only available outside the United States and have not been approved or cleared for marketing by the United States Food & Drug Administration.

PubMed listed publications – Orthopedics

Foot and Ankle

Extracorporeal shockwave therapy in patients with Morton’s Neuroma Hyun Seok , MD, PhD, Sang-Hyun Kim , MD, PhD, Seung Yeol Lee , MD, Sung Won Park , MD Journal of the American Podiatric Medical Association (2016)

Clinically relevant effectiveness of focused extracorporeal shock wave therapy in the treatment of chronic plantar fasciitis: a randomized, controlled multicenter study Gollwitzer, H; Saxena, A; DiDomenico, LA; Galli, L; Bouché, RT; Caminear, DS; Fullem, B; Vester, JC; Horn, C; Banke, IJ; Burgkart, R; Gerdesmeyer, L. The Journal of Bone and Joint Surgery (2015)

Two emerging technologies for achilles tendinopathy and plantar fasciopathy. Langer PR. Clinics in Podiatric Medicine and Surgery (2015)

Ultrasonographic evaluation of low energy extracorporeal pulse activated therapy (EPAT) for chronic plantar fasciitis. Gordon R, Wong C, Crawford EJ.  Foot & Ankle International (2012)

Comparison between extracorporeal shockwave therapy, placebo ESWT and endoscopic plantar fasciotomy for the treatment of chronic plantar heel pain in the athlete. Saxena A, Fournier M, Gerdesmeyer L, Gollwitzer H. Muscles, Ligaments and Tendons Journal (2012)

Successful treatment of chronic plantar fasciitis with two sessions of radial extracorporeal shock wave therapy. Ibrahim Ibrahim M, Donatelli R, Schmitz C, Hellman M, Buxbaum F. Foot & Ankle International (2010)

Comparison of radial versus focused extracorporeal shock waves in plantar fasciitis using functional measures. Lohrer H, Nauck T, Dorn-Lange NV, Schöll J, Vester JC. Foot Ankle International (2010)

Radial extracorporeal shock wave therapy is safe and effective in the treatment of chronic recalcitrant plantar fasciitis: results of a confirmatory randomized placebo-controlled multicenter study. Gerdesmeyer L, Frey C, Vester J, Maier M, Weil L Jr, Weil L Sr, Russlies M, Stienstra J, Scurran B, Fedder K, Diehl P, Lohrer H, Henne M, Gollwitzer HAmerican Journal of Sports Medicine (2008)

Extracorporeal shock wave therapy for chronic painful heel syndrome: a prospective, double blind, randomized trial assessing the efficacy of a new electromagnetic shock wave device. Gollwitzer H, Diehl P, von Korff A, Rahlfs VW, Gerdesmeyer L. Journal of Foot Ankle Surgery (2007)

Extracorporeal Shock Wave Therapy for the Treatment of Plantar Fasciitis Theodore GH, Buch M, Amendola A, Bachmann C, Fleming LL, Zingas C. Foot & Ankle International (2004)

Effect of shock-wave therapy on patellar tendinopathy in a rabbit model. Hsu RW, Hsu WH, Tai CL, Lee KF. Journal of Orthopedic Research (2004)

Ultrasonographic evaluation at 6-month follow-up of plantar fasciitis after extracorporeal shock wave therapy. Hammer DS, Adam F, Kreutz A, Rupp S, Kohn D, Seil R. Archives of Orthopaedic and Trauma Surgery (2003)

Shock wave therapy induces neovascularization at the tendon-bone junction: a study in rabbits. Wang CJ, Wang FS, Yang KD, Weng LH, Hsu CC, Huang CS, Yang LC. Journal of Orthopedic Research (2003)

Preliminary Results on the Safety and Efficacy of ESWT for Treatment of Plantar Fasciitis.  Alvarez R.  Foot & Ankle International (2002)

Achilles

Extracorporeal shock wave therapy improves the walking ability of patients with peripheral artery disease and intermittent claudication. Serizawa F, Ito K, Kawamura K, Tsuchida K, Hamada Y, Zukeran T, Shimizu T, Akamatsu D, Hashimoto M, Goto H, Watanabe T, Sato A, Shimokawa H, Satomi S. Japanese Circulation Journal (2012)

Extra-corporeal pulsed-activated therapy (“EPAT” sound wave) for Achilles tendinopathy: a prospective study.  Saxena A, Ramdath S Jr, O’Halloran P, Gerdesmeyer L, Gollwitzer H. The Journal of Foot & Ankle Surgery (2011)

Eccentric loading versus eccentric loading plus shock-wave treatment for midportion Achilles tendinopathy: a randomized controlled trial.  Rompe JD, Furia J, Maffulli N. American Journal of Sports Medicine (2009)

Eccentric loading compared with shock wave treatment for chronic insertional achilles tendinopathy: a randomized, controlled trial.  Rompe JD, Furia J, Maffulli N. The Journal of Bone and Joint Surgery (2008)

Eccentric loading, shock-wave treatment, or a wait-and-see policy for tendinopathy of the main body of tendon Achillis: a randomized controlled trial. Rompe JD, Nafe B, Furia JP, Maffulli N. American Journal of Sports Medicine (2007)

High-energy extracorporeal shock wave therapy as a treatment for insertional Achilles tendinopathy. Furia JP. The American Journal of Sports Medicine (2006)

Shock wave therapy for chronic Achilles tendon pain: a randomized placebo-controlled trial. Costa ML, Shepstone L, Donell ST, Thomas TL. Clinical Orthopedics and Related Research (2005)

Lower Extremity

The effectiveness of extracorporeal shock wave therapy in lower limb tendinopathy: a systematic review. Mani-Babu S, Morrissey D, Waugh C, Screen H, Barton C. American Journal of Sports Medicine (2014)

Vibration and pressure wave therapy for calf strains: a proposed treatment. Saxena A, St Louis M, Fournier M. Muscles, Ligaments and Tendons Journal (2013)

Ultrasonographic evaluation of low energy extracorporeal pulse activated therapy (EPAT) for chronic plantar fasciitis.  Gordon R, Wong C, Crawford EJ.  (Foot Ankle Int. Mar 2012)

High-energy focused extracorporeal shockwave therapy reduces pain in plantar fibromatosis (Ledderhose’s disease). Knobloch K, Vogt PM. BioMed Central Research Notes (2012)

Shockwave treatment for medial tibial stress syndrome in athletes; a prospective controlled study Moen MH, Rayer S, Schipper M, Schmikli S, Weir A, Tol JL, Backx FJ. British Journal of Sports Medicine (2011)

Shockwave therapy for the treatment of chronic proximal hamstring tendinopathy in professional athletes. Cacchio A, Rompe JD, Furia JP, Susi P, Santilli V, De Paulis F. The American Journal of Sports Medicine (2010)

Low-energy extracorporeal shock wave therapy as a treatment for medial tibial stress syndrome Rompe JD, Cacchio A, Furia JP, Maffulli N. American Journal of Sports Medicine (2009)

Extracorporeal shockwave for chronic patellar tendinopathy. Wang CJ, Ko JY, Chan YS, Weng LH, Hsu SL. The American Journal of Sports Medicine (2007)

Extracorporeal shock wave therapy in the treatment of chronic tendinopathies. Sems A, Dimeff R, Iannotti JP. Journal of the American Academy of Orthopaedic Surgeons (2006)

Effects of shock waves on the microcirculation in critical limb ischemia (CLI) (8-week study).  De Sanctis MT1, Belcaro GNicolaides ANCesarone MRIncandela LMarlinghaus EGriffin MCapodanno SCiccarelli R. Angiology (2000)

Pelvis and Hip

Home training, local corticosteroid injection, or radial shock wave therapy for greater trochanter pain syndrome. Rompe JD, Segal NA, Cacchio A, Furia JP, Morral A, Maffulli N. American Journal of Sports Medicine (2009)

Low-energy extracorporeal shock wave therapy as a treatment for greater trochanteric pain syndrome.  Furia JP, Rompe JD, Maffulli N. American Journal of Sports Medicine (2009)

Hand/ Wrist

Extracorporeal shock wave therapy in pillar pain after carpal tunnel release: a preliminary study. Romeo P, d’Agostino MC, Lazzerini A, Sansone VC. Ultrasound in Medicine and Biology (2011)

Extracorporeal shockwaves versus surgery in the treatment of pseudoarthrosis of the carpal scaphoid. Notarnicola A, Moretti L, Tafuri S, Gigliotti S, Russo S, Musci L, Moretti B. Ultrasound in Medicine and Biology (2010)

Elbow

Repetitive shock wave therapy for lateral elbow tendinopathy (tennis elbow): a systematic and qualitative analysis. Rompe JD, Maffulli N. British Medical Bulletin (2007)

Extracorporeal shock wave therapy without local anesthesia for chronic lateral epicondylitis. Pettrone FA, McCall BR. Journal of Bone and Joint Surgery (2005)

Safety and Efficacy of Extracorporeal Shock Wave Therapy for Chronic Lateral Epicondylitis.  Furia, JP.   The American Journal of Orthopedics (2005)

Repetitive low-energy shock wave treatment for chronic lateral epicondylitis in tennis players. Rompe JD, Decking J, Schoellner C, Theis C. American Journal of Sports Medicine (2004)

Shockwave therapy for patients with lateral epicondylitis of the elbow – A one to two year follow-up study. Wang CJ. American Journal of Sports Medicine (2002)

Upper Extremity

RADIAL EXTRACORPOREAL PRESSURE PULSE THERAPY FOR THE PRIMARY LONG BICIPITAL TENOSYNOVITIS.  Liu S1, Zhai L, Shi Z, Jing R, Zhao B, Xing G.  Ultrasound in Medicine and Biology (2012)

Extracorporeal shock wave therapy in the treatment of chronic tendinopathies. Sems A, Dimeff R, Iannotti JP. Journal of the American Academy of Orthopedic Surgeons (2006)

Shoulder

High-Energy Extracorporeal Shock-Wave Therapy for Treating Chronic Calcific Tendinitis of the Shoulder: A Systematic Review  Raveendhara R. Bannuru, MD; Nina E. Flavin, MD; Elizaveta Vaysbrot, MD, MS; William Harvey, MD, MSc; and Timothy McAlindon, MD, MPH. Annals of Internal Medicine (2014)

Calcific tendinitis of the shoulder. Diehl P, Gerdesmeyer L, Gollwitzer H, Sauer W, Tischer T. Orthopade – German (2011)

Effectiveness of radial shock-wave therapy for calcific tendinitis of the shoulder: single-blind, randomized clinical study Cacchio A, Paoloni M, Barile A, Don R, de Paulis F, Calvisi V, Ranavolo A, Frascarelli M, Santilli V, Spacca G. Physical Therapy (2006)

Extracorporeal shock wave therapy for the treatment of chronic calcifying tendonitis of the rotator cuff: a randomized controlled trial. Gerdesmeyer L, Wagenpfeil S, Haake M, et al.  The Journal of the American Medical Association (2003)

Radial shock wave therapy in calcifying tendinitis of the rotator cuff – a prospective study  Z Orthop Ihre Grenzgeb (2003)

Exact focusing of the extracorporeal shock wave therapy for calcifying tendinopathy. Haake M, Deike B, Thon A, Schmitt. Journal of Clinical Orthopaedics and Trauma (2002)

Spine and Back

Shock Wave Treatment Protects From Neuronal Degeneration via a Toll-Like Receptor 3 Dependent Mechanism: Implications of a First-Ever Causal Treatment for Ischemic Spinal Cord Injury.  Lobenwein D1, Tepeköylü C, Kozaryn R, Pechriggl EJ, Bitsche M, Graber M, Fritsch H, Semsroth S, Stefanova N, Paulus P, Czerny M, Grimm M, Holfeld J.  Journal of the American Heart Association (2015)

Mechano-transduction effect of shockwaves in the treatment of lumbar facet joint pain: Comparative effectiveness evaluation of shockwave therapy, steroid injections and radiofrequency medial branch neurotomy.  Nedelka T, Nedelka J, Schlenker J, Hankins C, Mazanec R.  (Neoro Enocrinology Letters 2014)

Bone

Biological mechanism of shockwave in bone.  Cheng JH, Wang CJ. International Journal of Surgery (2015)

Low-energy extracorporeal shock wave therapy as a treatment for medial tibial stress syndrome. Rompe JD, Cacchio A, Furia JP, Maffulli N.  American Journal of Sports Medicine (2010)

Extracorporeal shock-wave therapy compared with surgery for hypertrophic long-bone nonunions.Cacchio A, Giordano L, Colafarina O, Rompe JD, Tavernese E, Ioppolo F, Flamini S, Spacca G, Santilli V. Journal of Bone and Joint Surgery (2009)

Shock waves in the treatment of stress fractures. Moretti B, Notarnicola A, Garofalo R, Moretti L, Patella S, Marlinghaus E, Patella V. Ultrasound in Medicine and Biology (2009)

The effects of extracorporeal shock wave in acute high-energy long bone fractures of the lower extremity. Wang, CJ et al.  Archives of Orthopaedic and Trauma Surgery (2006)

Treatment for osteonecrosis for the femoral head: comparison of extracorporeal shock waves with core decompression and bone-grafting. Wang, CJ et al. The Journal of Bone and Joint Surgery (2005)

Effect of shock wave therapy on acute fractures of the tibia: a study in a dog model. Wang CJ, Huang HY, Chen HH, Pai CH, Yang KD.  Clinical Orthopaedics and Related Research (2001)

Treatment of nonunions of long bone fractures with shock waves C. Wang, MD. Clinical Orthopaedics and Related Research (2001)

Myofascial Trigger Points

Trigger points – Diagnosis and treatment concepts with special reference to extracorporeal shockwaves (German). Gleitz M, Hornig K. Orthopade (2012)

Shock wave therapy of trigger points in the masticatory muscles.  Gleitz M, Hornig K. Orthopade (Feb 2012)

Non-PubMed publications/papers

Influence of medical shockwaves on healthy muscle tissue.  Vincent KC, d’Agostino C, Schaden W, Karalus P, Grant L.  European Congress of Sports Medicine (2016) 

The Effectiveness of Extracorporeal Shock Wave Therapy (ESWT) in the Management of Trigger Finger LUK MLM, CHO JSY, NG DMT, POON MC, LAU PMY. Physiotherapy Department, Queen Elizabeth Hospital. Hospital Authority Convention (2014)

Extracorporeal Pulse Activation Technology in Acute and Chronic Musculoskeletal Pain of the Lower Extremity: A case series.  Iorio A, Rode K., Hart B. NYCPM (2009)

A neural model for chronic pain and pain relief by extracorporeal shock wave treatment. Wess, OJ. Urol Res (2008)

Assorted Abstracts. Markus Gleitz. (2003-2008)